Methylphenidate and if-then plans are comparable in modulating the P300 and increasing response inhibition in children with ADHD
A disturbed functioning of the prefrontal cortex, the anterior cingulate cortex, and an accordingly reduced P300 presumably underlies executive function deficits of children with attention deficit hyperactivity disorder (ADHD). Using a combined classification and Go/ NoGo task paradigm, the present study investigated whether medication with methylphenidate (MPH) modulates the P300 as measured by a high-density electroencephalogram (EEG) and facilitates response inhibition in children with ADHD. Further, effects of MPH were compared with effects of self-regulation by if-then plans (Gollwitzer in Am Psychol 54: 493–503, 1999). MPH as well as if-then plans modulated the P300 and improved inhibition of an unwanted response on a Go/NoGo task to the same level observed in children without ADHD. Importantly, selfregulation strategies might be a valuable alternative to medication with MPH in children with ADHD.
|Autor:||I. Paul-Jordanov, M. Bechtold & C. Gawrilow|
|Quelle:||ADHD Atten Def Hyp Disord (2010) 2:115–126|
|Keywords (englisch):||ADHD, EEG, P300, Methylphenidate, Implementation intentions|