The World Federation of ADHD International Consensus Statement: 208 Evidence-based Conclusions about the Disorder

Stephen V Faraone, Tobias Banaschewski, David Coghill, Yi Zheng, Joseph Biederman, Mark A Bellgrove, Jeffrey H Newcorn, Martin Gignac, Nouf M Al Saud, Iris Manor, Luis Augusto Rohde, Li Yang, Samuele Cortese, Doron Almagor, Mark A Stein, Turki H Albatti, Haya F Aljoudi, Mohammed M J Alqahtani, Philip Asherson, Lukoye Atwoli, Sven Bölte, Jan K Buitelaar, Cleo L Crunelle, David Daley, Søren Dalsgaard, Manfred Döpfner, Stacey Espinet, Michael Fitzgerald, Barbara Franke, Manfred Gerlach, Jan Haavik, Catharina A Hartman, Cynthia M Hartung, Stephen P Hinshaw, Pieter J Hoekstra, Chris Hollis, Scott H Kollins, J J Sandra Kooij, Jonna Kuntsi, Henrik Larsson, Tingyu Li, Jing Liu, Eugene Merzon, Gregory Mattingly, Paulo Mattos, Suzanne McCarthy, Amori Yee Mikami, Brooke S G Molina, Joel T Nigg, Diane Purper-Ouakil, Olayinka O Omigbodun, Guilherme V Polanczyk, Yehuda Pollak, Alison S Poulton, Ravi Philip Rajkumar, Andrew Reding, Andreas Reif, Katya Rubia, Julia Rucklidge, Marcel Romanos, J Antoni Ramos-Quiroga, Arnt Schellekens, Anouk Scheres, Renata Schoeman, Julie B Schweitzer, Henal Shah, Mary V Solanto, Edmund Sonuga-Barke, César Soutullo, Hans-Christoph Steinhausen, James M Swanson, Anita Thapar, Gail Tripp, Geurt van de Glind, Wim van den Brink, Saskia Van der Oord, Andre Venter, Benedetto Vitiello, Susanne Walitza, Yufeng Wang (2021)

Neuroscience & Biobehavioral Reviews 128, 789-818

Abstract

Background: Misconceptions about ADHD stigmatize affected people, reduce credibility of providers, and prevent/delay treatment. To challenge misconceptions, we curated findings with strong evidence base. Methods: We reviewed studies with more than 2,000 participants or meta-analyses from five or more studies or 2,000 or more participants. We excluded meta-analyses that did not assess publication bias, except for meta-analyses of prevalence. For network meta-analyses we required comparison adjusted funnel plots. We excluded treatment studies with waiting-list or treatment as usual controls. From this literature, we extracted evidence-based assertions about the disorder. Results: We generated 208 empirically supported statements about ADHD. The status of the included statements as empirically supported is approved by 80 authors from 27 countries and 6 continents. The contents of the manuscript are endorsed by 403 people who have read this document and agree with its contents. Conclusions: Many findings in ADHD are supported by meta-analysis. These allow for firm statements about the nature, course, outcome causes, and treatments for disorders that are useful for reducing misconceptions and stigma.

Categories: ADHS Allgemein, Diagnostik, Therapie

Keywords: ADHD, diagnosis, treatment, course, outcome, genetics, brain

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