Pharmacological interventions for ADHD: a systematic review and dose-effect network meta-analysis

M. Nourredine, L. Jurek, T. Hamza, et al. (2026)

The Lancet Psychiatry 13(6), 485-495

Abstract

First dose-effect network meta-analysis of ADHD medications. Efficacy plateaus were identified for methylphenidate, amphetamines and guanfacine, with dose-dependent increases in discontinuation due to adverse events.

Categories: Medikamente, Therapie

Keywords: dose-response, titration, maximum dose, methylphenidate, amphetamines, guanfacine

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